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| Wedged hepatic vein pressure ： ウィキペディア英語版 |
Portal venous pressure
Portal venous pressure is the blood pressure in the hepatic portal vein, and is normally between 5-10 mmHg.〔(eMedicine - "Esophageal Varices" )〕 Raised portal venous pressure is termed portal hypertension,〔(Ascites in Cirrhosis Relative Importance of Portal Hypertension and Hypoalbuminemia ) DONALI) O. CASTELL, LCDR (MC), USN〕 and has numerous sequelae such as ascites and hepatic encephalopathy.
==Wedged hepatic venous pressure (WHVP)==
WHVP is used to estimate the portal venous pressure by reflecting not the actual hepatic portal vein pressure but the hepatic sinusoidal pressure. It is determined by wedging a catheter in a hepatic vein, to occlude it, and then measuring the pressure of proximal static blood (which is reflective of pressure in the sinusoids). WHVP in fact slightly underestimates portal pressure due to sinusoidal equilibration in patients without cirrhosis, but the difference between the two is clinically insignificant. In patients with cirrhotic livers intersinusoidal communication is disrupted such that sinusoidal pressure equilibrium cannot be maintained, and so WHVP becomes a far more accurate measure of portal venous pressure.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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